Researchers Discover Specific Ways Marijuana Affects Brain Receptors in Recent Study

Researchers have officially confirmed that when people use marijuana, certain malfunctions occur within the cannabinoid brain receptors – resulting in a clearer picture of how to treat people with marijuana addictions. They also collected evidence that the damage to brain receptors may be reversible if the marijuana use is ended.

The research, conducted by the National Institute of Mental Health together with the National Institute on Drug Abuse, shows how a person’s ability to experience pleasure, to focus on a task, to understand the passage of time and to remember or have coordinated movements is affected by marijuana. The active chemical found in marijuana, THC, adheres to cannabinoid receptors at the brain level and impairs these functions, in addition to cannabinoid receptors found elsewhere in the systems related to digestion, breathing and cardiovascular health.

During the study, researchers looked at biological processes of 30 marijuana users for a month, using PET scanning and injections that allowed a view of how the marijuana was affecting their bodies.

When the half of the participants stopped using marijuana, they were examined again, according to a recent study report. Results showed that the receptor activity in the brain had jumped significantly without the marijuana usage, in comparison with receptor activity when the research started. Researchers summarized that marijuana causes reduced activity of certain receptors responsible for body processes and functions, but that with a cessation of marijuana use, this activity can return.

Further implications from the study include the importance of using PET imaging for studying several types of human illness.